Genomics Now

Series 3 Episode 5: Family Implications of Genomic Test results

Speakers: Dr. Dahlia Hopmeier and Dr. Helen Grote
This episode addresses the various implications that genomic test results may have for a patient, as well as their family members. It focuses on the challenges that may arise with regards to sharing of information, and the ways in which families can be supported throughout this process.
Recorded in June 2021

Series 3 Episode 4: Fetal Exome Sequencing

Speakers: Dr. Dahlia Hopmeier and Dr. Rhiannon Melis
This episode explores the various ways in which fetal DNA can be examined, including fetal exome sequencing. The clinical utility and how this fits into NHS testing pathways is also discussed.
Recorded in June 2021

Series 3 Episode 3: Non-invasive Prenatal Testing (NIPT)

Speakers: Dr. Dahlia Hopmeier and Dagmar Tapon
This episode explains the concept of non-invasive prenatal testing (NIPT) and the roll-out of this technique as an additional testing option in the NHS.
Recorded in June 2021

Series 3 Episode 2: Rare Disease Genomics in 10 Minutes

Speakers: Dr. Dahlia Hopmeier and Dr. Angela Brady
In this episode the role of genomics in rare disease is discussed, and explanations of genomic variants and how they are identified and interpreted are given.
Recorded in June 2021

Series 3 Episode 1: Cancer Genomics in 10 Minutes

Speakers: Dr. Dahlia Hopmeier and Dr. Angela Brady
This episode gives a brief overview of the role of genomics in cancer and explains key concepts including familial cancer syndromes and diagnostic versus predictive gene testing.
Recorded in June 2021

Series 2 Episode 5: Pharmacogenomics

Speakers: Dr. Dahlia Hopmeier and Dr. Anwar Khan
In this episode the concept of pharmacogenomics is explained along with examples of pharmacogenomics already in use by the NHS. The role of pharmacogenomics in general practice and predictions for the future are also discussed.
Recorded in May 2021

Series 2 Episode 4: Simple Explanations on Genomics for Patients

Speakers: Dr. Dahlia Hopmeier and Dr. Anwar Khan
This episode focuses on simple explanations on genomics for patients to enable primary care practitioners to discuss genomics in their daily practice.
Recorded in May 2021.

Series 2 Episode 3: Direct-to-consumer Tests

Speakers: Dr. Dahlia Hopmeier and Dr. Anwar Khan
This episode explains the variability of direct-to-consumer tests and the potential limitations and risks. The role of the GP in interpreting results from these tests is explored, with reference to the Royal College of General Practitioner’s position statement.
Recorded in May 2021

Series 2 Episode 2: Clinical Genomics

Speakers: Dr. Dahlia Hopmeier and Dr. Anwar Khan
This episode gives examples of the most common genomic diseases and genomic “red flags” that GPs may encounter, and touches upon what should prompt them to “think genetics”, or to consider referral for further genetic assessment.
Recorded in May 2021.

Series 2 Episode 1: The Role of Genomics in Primary Care

Speakers: Dr. Dahlia Hopmeier and Dr. Anwar Khan
In this episode the role of genomics in primary care is discussed, Examples of scenarios that GPs may encounter in their practice are given, and the role of the GP in increasing genomic testing and diagnosis is explored.
Recorded in May 2021

Series 1 Episode 5: Which genomic test and when - rare disease and cancer

Speakers: Shazia Mahamdallie and Dr. Dahlia Hopmeier
In this episode we explain some of the information to consider that can help guide healthcare professionals in choosing the appropriate genome-based test for patients, this in the context of conditions such as rare disease or cancer.
Recorded in June 2021.

Series 1 Episode 4: What are Genomic Laboratory Hubs and the National Test Directory?

Speakers: Shazia Mahamdallie and Dr. Dahlia Hopmeier
In this episode we concentrate on exploring the purpose of two of the Genomic Medicine Service’s components, the Genomic Laboratory Hubs (GLHs) and the National Test Directory.
Recorded in June 2021

Series 1 Episode 3: The Genomic Medicine Service and the associated GMS Alliances

Speakers: Shazia Mahamdallie and Dr. Dahlia Hopmeier
In this episode we explore how NHS England’s Genomic Medicine Service is practically bringing genomic testing into routine clinical care and how the role of the associated Genomic Medicine Service Alliances are working together to both embed and realise the potential of genomic testing across the health service.
Recorded in June 2021

Series 1 Episode 2: What did the 100,000 Genomes Project bring to the NHS?

Speakers: Shazia Mahamdallie and Dr. Dahlia Hopmeier
In this episode we explain what the 100,000 Genomics Project was and how this research Project paved the way for genome-based testing to become part of routine care in the NHS.
Recorded in June 2021

Series 1 Episode 1: Genomic testing in the NHS

Speakers: Shazia Mahamdallie and Dr. Dahlia Hopmeier
In the episode we explain the basics of genes, genomes, genetics and genomics. We explore the difference between genetics and genomic testing, and how they have evolved in the NHS.
Recorded in June 2021